If you are using BT BROADBAND exit the BT Broadband help icon in bottom right corner of desktop and the problem will go away

If you are using BT Broadband delete the help icon in the bottom right corner of the desktop and the problem will go away

It appears to have started after my last itunes update.but as mentioned earlier got to your programs and features icon on your control panel and uninstal the apple mobile support from the list and you should be up and running again.

The thing that makes me crazy is after spending hours on the phone with iphone tech support they say it is a vista problem, or something in my computer, NOT an itunes bug. Well, that doesn't sound right to me or i bet to all these users who have posted the same problem. Is Apple working on this? They say they haven't heard of this problem before me, HA!

This seems to be another User Account Control Problem. Installing iTunes (after first uninstalling the old version)with the UAC turned on works. No messages about the mobile device helper. As soon as the UAC is turned off, however, the annoying dialogue box appears every 8-9 seconds, though it does not interfere with synchronizing either the iPod Classic or the iTouch. I had exactly the same UAC problem with a Franklin Covey Program for Outlook when I first got the Vista system. The FC program worked with the UAC on,but not off. Since Quicken required just the opposite (UAC off) to access its data files, I opted to keep the UAC off. I am the only user of my computer and I need access to Quicken more than I care about the FC program. As I recall, Adobe Acrobat needed the UAC off in order to download and install, so it seems clear that some programmers do something that demands one thing or another of the UAC, while other programmers write programs that are independent of the UAC status.
In the case of iTunes and Quicken there is no easy way out because I want easy access to both - and turning the UAC on and off (Go to Control panel, User Accounts to find your UAC) requires full system restarts. I tried to post this answer on an Apple forum site, but in typical Apple fashion, the registration page couldn't recognize that I had filled out the form. In the meantime, I am appealing to Intuit to see if they have a solution for Quicken's difficulty with the UAC - at least one can send them a a message (if anyone knows how to send Apple a message, please feel free to forward this.)

After reading the Wall Street Journal description of MobileMe, I realized that it may have been installed with the latest version of iTunes. Sure enough, it is was in the startup file, and when I unchecked it, the mobile device helper message disappeared from iTunes, even with the User Account control turned off.
You can find your start up menu by typing msconfig in the search box, clicking on the icon that appears, and then navigating to the start up file. I unchecked a number of other programs that had been installed with downloaded software,including iTunes itself. I'm OK with manually starting it.

Yahoo!!
I uninstalled "apple mobile device helper support" under pregrams and features, and lo I'm back in business with itunes. Thanks to unregistered guest for your input. We're happy now.

DR

Thank you for the BT Broadband suggestion - to remove the help icon from the desktop - what a simple solution!!!
Fi

i did the whole runing as adminstrator and it stoped popping up but now i need help to sync to my ipod touch the button is not avilable i cant click on it!!! NEED HELP PLEASE

Wow! Thanks alot Bill. I finally was able to sync my new iphone.