I have installed Vista Home Edition. Until now i was using Nod32 antivirus NOD32 Free Download - Antivirus protection and malware detection and i don't was very satisfied. It is any possibility to run 2 antivirus programs in the same time on Vista ?

You probably could but why would you want to? They'd probably conflict somewhere down the line plus it would eat up on you resources big time.. (especially if you like playing games)
Have you considered AVG? It's free and does an excellent job

Check out this thread here:
http://winvistaforums.com/windows-vi...nti-virus.html

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What he said