Hi Tyro, I would think the AVG anti virus would still work but there is another complete solution that I'm hearing good things about.

Since your running Vista Home which I assume is the 32 bit version check out the link below.
ESET NOD32 and Strike Down Malware
ESET NOD32: Antivirus Software

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Thanks,
Nolan

Specs: Running at 3ghz w/stock voltages
COOLER MASTER RC-690 Case
CORSAIR 620HX
GIGABYTE GA-P35-DS4
CPU,Q6600 G0
2GB PC6400 DUAL BALLISTIX LINE
EVGA 8800GT SC
Asus Silent Square 3-in-1 CPU Cooler
DVD SAMSUNG|SH-S203B
SAMSUNG 500G SATA2 3Gb/s
WD 500GB SATA2 3Gb/s
Seagate 320GB SATA2 3Gb/s
3ea - 120mm Yate Loon Cooling Fans
Sunbeam CW-BK 5.25" Fan Controller
SAMSUNG 226BW 22" Monitor
Logitec G15 keyboard
Logitec MX518 Mouse
Vista Ultimate 64-bit OEM