I only turn off UAC,Defender,Shadow Storage (System Restore),Remote differential compression, Tablet PC, and I untick 'animate windows when minimising and maximising' as I like mine to 'snap' open rather than slide into view. I also disable one or two other things like parental control, fax ect but the biggest boost I found was buying another GB of RAM! Running Vista with 2GB is the only way to go if you want it to be fast and still keep things like indexing and search. Prices for DDR2 are now rock bottom so it's not so expensive to upgrade and the performance increase is amazing.

__________________